师资队伍

硕士生导师

徐黎个人简介

作者: 来源: 阅读次数: 日期:2025-02-26

姓名:徐黎

出生年月:198702

学历/学位:博士研究生

职称:副教授

邮箱:2997@hbucm.edu.cn

教育经历:

2009/09 — 2014/12 武汉大学化学与分子科学学院专业,有机化学,博士

2005/09 — 2009/06 武汉大学化学与分子科学学院专业,化学类,学士

工作经历:

2021/12-至今 湖北中医药大学药学院,副教授

2015/07 — 2021/12 湖北中医药大学药学院,讲师

教学与科学研究:

研究领域:(1)光学材料及检测;(2)纳米制剂

讲授课程:(1)本科生课程:《物理化学学》

主持/参与主要科研项目:

1. 国家自然科学基金青年项目,51903081,热活化延迟荧光材料敏化的高效率红光磷光纳米粒子的设计、合成及其时间分辨成像应用,2019/01-2021/12,23万元,主持;

2. 湖北省部级科研项目,2019CFB228,基于AIE材料的信号放大体系用于“PCR-Free”核酸检测,2019/01-2020/12,5万元,主持;

3. 湖北省教育厅科研计划项目,Q20192001,自由基聚合介导的聚集发光信号放大体系用于核酸检测,2019/01-2020/12,2万元,主持;

7. 国家自然科学基金面上项目,21974636,针型场效应晶体管生物传感器的研制及其用于活体信号分子实时监测,60万,参与;

8. 国家自然科学基金面上项目,82173960,基于TLR2-MyD88-MAPK/NF-κB信号通路的高良姜抗

H.pylori胃炎药效物质及作用机制研究,55万,参与;

9. 横向项目,SZZC-2023-0148,中药材样品采集和制备项目,98万元,参与;,

已发表的部分研究成果:

1. Luo, R.; Xu, L.; Chen, J.; Zhang, W.; Feng, S.; Qiu, Z.; Hong, Y.; Feng, G. Analytical Chemistry 2025, 97, 1719.(中科院1区,IF = 8)

2. Chen, J.; Luo, R.; Li, S.; Shao, J.; Wang, T.; Xie, S.; Xu, L.*; You, Q.*; Feng, S.*; Feng, G.*, A novel NIR fluorescent probe for copper(ii) imaging in Parkinson's disease mouse brain. Chemical Science 2024, 15 (32), 13082-13089.(中科院1区,IF = 8)

3. Li, Y.; Wang, Y.; Wu, Q.; Qi, R.; Li, L.; Xu, L.*; Yuan, H.*, High-throughput fluorescence sensing array based on tetraphenylethylene derivatives for detecting and distinguishing pathogenic microbes. Spectrochimica Acta Part A 2024, 318.(中科院2区,IF = 4. 38)

4. Zhu, Z. *; Luo, Z.; Xie, Y.-Q.; Sun, Y.; Xu, L.*; Wu, Q.*, Highly Efficient Red Thermally Activated Delayed Fluorescence Nanoparticles for Real-Time in Vivo Time-Resolved Luminescence Imaging. Adv. Funct. Mater. 2023, 2313701.(中科院1区, IF = 18.808 )

5. Yuan, H.; Li, Z.; Zhao, Q.; Jia, S.; Wang, T.; Xu, L. *; Yuan, H. *; Li, S. *, Molecular Evolution of Acceptor–Donor–Acceptor‐type Conjugated Oligomer Nanoparticles for Efficient Photothermal Antimicrobial Therapy. Adv. Funct. Mater. 2023, 33 (21),2213209. (中科院1区, IF = 18.808)

6. Zhao, Y.; Cui, Y.; Xie, S.; Qi, R.; Xu, L.*; Yuan, H.*, Halogen atom regulation of acceptor–donor–acceptor type conjugated molecules for photothermal antibacterial and antibiofilm therapy. Biomaterials Science 2024, 12 (17), 4386-4392.

7. Luo, Z.; Zhou, Z.; Pan, Y.; Zhu, Z.; Yuan, H.*; Li, Y.; Feng, S.; Hong, Y.; Xu, L.*, Cell-penetrating peptides noncovalently modified red phosphorescent nanoparticles for high-efficiency imaging. RSC Advances 2024, 14 (17), 11891-11899.

8. Li Xu*, Zhuo Chen, Fangdan Zhang, Zihan Luo, Shijia Zheng, Zece Zhu*, Bin-g Huang. The cis configuration of amino-modified tetraphenylethene for selective det-ection of single-stranded guanine-rich DNA. Spectrochimica Acta Part A, 2022, 272, 120987. (中科院2,IF = 4. 38)

9. Jia, S.; Li, Z.; Shao, J.; Yuan, H. *; Li, L.; Xu, L.*, Acceptor Regulation of Acceptor–Donor–Acceptor Type Conjugated Oligomer for Photothermal Combating of Resistant Bacteria. ACS Applied Polymer Materials 2022, 4 (8), 5275-5280. (中科院2区,IF = 4.4)

10. Li Xu*, Zhuo Chen, Fangdan Zhang, et al. The cis configuration of amino-modified tetraphenylethene for selective detection of single-stranded guanine-rich DNA. Spectrochimica Acta Part A, 2022, 272, 120987.(中科院2区,IF = 4. 38)

11. Li Xu*, Zhuo Che, Fangdan Zhang, et al. The cis configuration of amino-modified tetraphenylethene for selective detection of single-stranded guanine-rich DNA. Spectrochimica Acta Part A, 2022, 272, 120987.(中科院二区,IF = 4. 38)

12. Zhai Yanke, Pan Yixing, Xaing hao, Xu Li*, Zhu zece, Lei Me. DSAZn与槲皮素的配位结合及对槲皮素的高灵敏度检测. 光谱学. 核心期刊

13. Li Z, Xu L, Yuan H, Zhang, P. Fluorescent sensor array based on aggregation-induced emission luminogens for pathogen discrimination. Analyst. 2022,147,2930-2935(中科院 三区,IF = 4.616)

14. Xu, Li*, Wang, Jin Luo, Qingqing, Chen, Guangcai, Ni, Fan, Zhu, Zece*, Zhao, Qiang*, Zhang, Guo-Jun, Yang, Chuluo*. Highly Emissive Phosphorescence Nanoparticles Sensitized by a TADF Polymer for Time-resolved Luminescence Imaging. Mater. Chem. Front., 2020, 4, 2389(基础版中科院一区,IF= 6.9)

15. Di Tian, Zece Zhu*, Li Xu*, Hengjiang Cong, Jintao Zhu* Intramolecular Electronic Coupling for Persistent Room- Temperature Luminescence for Smartphone Based Time-Gated Fingerprints Detection. Materials Horizons,2019,6, 1215-1221 .(中科院一区,IF= 14.356)

16. Li Xu, Danqing Wei, Zece Zhu, and Chuluo Yang," Nucleic acid probe and stain based on water-soluble tetraphenylethene derivatives modified with different kinds of amino binding groups: the role of hydrogen bond ",Sens. Actuators, B,2016, 234,521-526.(中科院一区,IF= 4.079)

17. Li Xu,Zece Zhu, Xiang Zhou, Jingui Qin,and Chuluo Yang, "A highly sensitive nucleic acid stain based on amino-modified Tetraphenylethene: the influence of configuration",Chem. Commun., 2014, 50, 6494–6497.(中科院二区,IF= 6.834)

18. Li Xu,Zece Zhu, Danqing Wei, Jingui Qin,and Chuluo Yang, "Amino-Modified Tetraphenylethene Derivatives as Nucleic Acid Stain: Relationship between the Structure and Sensitivity", ACS Appl. Mater. Interfaces, 2014, 6, 18344–18351.(中科院一区,IF= 7.145)

19. 第一发明人专利2020年获得授权,“酶引发的自由基聚合反应及检测应用”,专利号:ZL201610122276.6

20. 第一发明人专利2021年获授权,“一种长寿命发光纳米粒子及其制备方法和应用”,专利号:ZL 201910112592.9

21. 第一发明人专利2023年获授权,“一种荧光检测信号放大体系”,专利号:ZL 202010139105.0


1. 陈广才等,2021年湖北省第十三届“挑战杯”大学生课外学术科技作品竞赛,二等奖;